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. 2021 May 28;12:704503. doi: 10.3389/fphar.2021.704503

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Copyright © 2021 Karim, Alkreathy, Ahmad and Khan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Nitric Oxide (NO) levels (A) and Nitric Oxide synthase (NOS) activity (B) in skin homogenate following treatments with diabetic control (G1), Vehicle (G2), SPPE gel (G3) Values are represented as mean ± SEM (n = 6).