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. Author manuscript; available in PMC: 2021 Jun 11.
Published in final edited form as: Pediatr Obes. 2020 Dec 11;16(6):e12759. doi: 10.1111/ijpo.12759

Fig 2. Effects of excessive fructose consumption on biological pathways that contribute to increased risk of NAFLD development and progression in children and adolescents.

Fig 2.

As discussed in the text, high intake of added sugar or fructose has been associated with increased DNL, hepatic insulin resistance (IR), hyperuricemia, hepatic inflammation, oxidative stress, and visceral adiposity. High fructose intake has also been associated with gut dysbiosis.