FIGURE 2.

Diet-related alteration of fatty acid profiles in feces of breastfed (B, blue) and formula-fed infants without (F-, orange) or with probiotics (F⁺, green) over time. (A) Myristic, (B) arachidonic and (C) eicosapentaenoic acid were increased in group B up to month 7. Peak areas exceeding 10*mean for individual fatty acid were excluded from plotting procedure for a better visualization. (D) Detection of six different human milk oligosaccharides (HMOs) in breast milk and infant feces. Breast milk samples were categorized in secretor (n = 35, dark-blue) and non-secretor (n = 7, light-blue). Breast milk (n = 42) and feces samples (n = 39) were mother-child and time (m1, 3) matched for comparison. The secretor status determined the relative amount of different HMOs in breast milk as well as in the corresponding feces samples. Significance was calculated in each month between B, F− and F+ group using the Kruskal-Wallis rank sum test or Wilcoxon rank sum test for comparing secretor and non-secretor status. ns: p > 0.05, *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001, ****p ≤ 0.0001.