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. 2021 May 28;12:651056. doi: 10.3389/fimmu.2021.651056

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Copyright © 2021 Hu, Wu, Liu and Chen

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Validation of the effectiveness of immune subtypes. (A–D) The boxplot showed that there was a statistical difference in Immune Score, Stromal Score, ESTIMATE Score, and Tumor Purity between the two immune infiltration subtypes (P<2.2e-16). (E–G) The gene expression level of the gene set, including major histocompatibility complex (MHC), immune co-inhibitor checkpoints (IAP), and immune co-stimulator checkpoints (ICP) were all significantly different in the two immune infiltration subtypes (P<0.05).