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. 2021 Jun 1;17(6):e1009044. doi: 10.1371/journal.pcbi.1009044

Fig 2. Application to the TCGA data from multiple cancers.

Fig 2

(A) Number of cancer patients or samples on 33 cancer types from TCGA in this study. (B) Correlation between the modularity scores of identified modules (y-axis) and the corresponding singular values (objective function values) (x-axis) with PCC r = 0.98. (C) Distribution of modularity scores. The modularity scores of identified modules are significantly greater than those of random ones (Permutation test P < 0.05/50 for each identified module). (D) Among the 1793 genes from all the identified modules, 328 are reported to be related with cancer (Hypergeometric test P = 1.47e-06). (E) Among the 122 miRNAs from all the identified modules, 73 are reported to be related with cancer (Hypergeometric test P = 3.38e-03).