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. 2021 Jun 11;16(6):e0249382. doi: 10.1371/journal.pone.0249382

Table 1. Summary statistics of studies analyzed.

P. falciparum P. vivax
Number of studies 153 54
Number of data points1 275 115
Number of surveyed individuals 105609 39671
Number of genotyped individuals 33526 13325
Method for diagnosis of infection2
Microscopy/RDT 180 (66.4%) 61 (51.7%)
PCR 91 (33.6%) 57 (48.3%)
Number of genotyping markers2
1 marker 133 (49.1%) 11 (9.4%)
>1 marker 138 (50.9%) 106 (90.6%)
Method for genotyping2
Size polymorphic - gel 214 (79.0%) 18 (15.4%)
Size polymorphic - CE 51 (18.8%) 89 (76.1%)
SNP panel 1 (0.4%) 1 (0.9%)
Amplicon sequencing 5 (1.8%) 4 (3.4%)
WGS 0 (0.0%) 5 (4.3%)
Clinical symptoms2
Asymptomatic 120 (44.3%) 26 (22.0%)
Clinical 151 (55.7%) 92 (78.0%)
Age range2
All ages 162 (59.8%) 102 (86.4%)
<15 years 92 (34.0%) 7 (5.9%)
>15 years 17 (6.3%) 9 (7.6%)
Geographic region2
Africa 214 (79.0%) 11 (9.3%)
Asia-Pacific 51 (18.8%) 84 (71.2%)
Latin America 6 (2.2%) 23 (19.5%)
Mean proportion of polyclonal infections [range] 57.0% [0–98.9] 42.8% [0–100]
Mean MOI [range] 2.26 [1–6.1] 1.59 [1–3.8]

Table 1: Characteristics of studies analyzed.

1 Multiple data points were retrieved from a study if data was reported separately for different locations, age groups, time points, or separately for clinical and asymptomatic individuals.

2 For each factor, the number and percentage of data points is given.