Table 3. Multivariable predictors of A) P. vivax proportion of polyclonal infections, and B) mean multiple clone infections.

95%CI = 95% confidence interval.

A) P. vivax proportion of polyclonal infections
	Full model		Reduced model
	Coef [95%CI]	P	Coef [95%CI]	P
Prevalence	0.476 [-0.004, 0.955]	0.052	0.479 [0.037, 0.921]	0.034
Year	-1.375 [-2.483, -0.266]	0.016	-1.274 [-2.345, -0.202]	0.02
Sizing by CE	6.301 [-10.692, 23.294]	0.463
>1 genotyping marker	29.408 [0.018, 58.798]	0.05	35.421 [10.294, 60.548]	0.006
PCR for diagnosis	3.81 [-6.633, 14.253]	0.47
Geographic Region
Africa	[reference]		[reference]
Asia-Pacific	10.301 [-15.537, 36.139]	0.0135	9.584 [-15.463, 34.631]	0.0141
Latin America	-7.299 [-33.845, 19.248]		-7.45 [-33.437, 18.537]
Age group
All	[reference]		[reference]
<15	1.845 [-16.029, 19.719]		2.658 [-14.916, 20.231]	0.0134
>15	-30.677 [-50.749, -10.606]	0.0109	-29.072 [-48.705, -9.439]
Presence of clinical symptoms	5.521 [-6.186, 17.228]	0.351
B) P. vivax mean multiplicity of infections
	Full model		Reduced model
	Coef [95%CI]	P>t	Coef [95%CI]	P>t
Prevalence	0.019 [0.009, 0.029]	<0.001	0.019 [0.009, 0.029]	<0.001
Year	-0.04 [-0.061, -0.019]	<0.001	-0.039 [-0.059, -0.019]	<0.001
Sizing by CE	-0.045 [-0.39, 0.301]	0.798
>1 genotyping marker	0.434 [0.004, 0.865]	0.048	0.403 [0.096, 0.711]	0.011
PCR for diagnosis	-0.027 [-0.216, 0.162]	0.775
Geographic Region
Africa	[reference]		[reference]
Asia-Pacific	0.165 [-0.203, 0.534]	0.0108	0.173 [-0.182, 0.527]	0.0068
Latin America	-0.238 [-0.653, 0.177]		-0.225 [-0.62, 0.17]
Age group
All	[reference]		[reference]
<15	0.193 [-0.171, 0.556]	0.0167	0.193 [-0.162, 0.548]	0.0136
>15	-0.482 [-0.85, -0.115]		-0.477 [-0.832, -0.122]
Presence of clinical symptoms	-0.018 [-0.239, 0.203]	0.869