Table 1.
Baseline characteristics and unadjusted differences between patients with IEP and BS
| Variables | All patients | IEP | BS | P value |
|---|---|---|---|---|
| (n = 960) | (n = 576) | (n = 384) | ||
| Age, years (mean ± SD) | 64 (18) | 63 (18) | 64 (17) | 0.320 |
| Gender: male, n (%) | 617 (65) | 333 (58) | 284 (74) | < 0.001 |
| Location perforation, n (%) | < 0.001 | |||
| Proximal | 362 (38) | 296 (52) | 66 (17) | |
| Distal | 594 (62) | 279 (49) | 315 (83) | |
| Initial treatment, n (%) | ||||
| Surgery | 501 (52) | 269 (47) | 232 (60) | < 0.001 |
| Endoscopy | 191 (20) | 139 (24) | 52 (14) | < 0.001 |
| Conservative only | 194 (20) | 138 (24) | 56 (15) | < 0.001 |
| Surgery and endoscopy | 73(8) | 30 (5) | 43 (11) | 0.001 |
| Outcome | ||||
| Overall mortality, n (%) | 120 (13) | 55 (10) | 65 (17) | 0.001 |
| ICU admission, n (%) | 531 (68) | 264 (57) | 267 (86) | < 0.001 |
| Re-intervention, n (%) | 289 (32) | 143 (26) | 146 (40) | < 0.001 |
| LOS, median days (IQR) | 18 [9–35] | 15 [8–28] | 27 [13–47] | < 0.001 |
Values represent number of patients (percentage of total in column) [n (%)], mean (SD), or median (IQR). Bold p-values indicate that differences between the groups were statistically significant
n number of patients, SD standard deviation, IEP iatrogenic esophageal perforation, BS Boerhaave’s syndrome, ICU intensive care unit, LOS length of hospital stay, TOD time of diagnosis, IQR interquartile range