Table 2.

Differential diagnosis of leukocytoclastic vasculitis

Noninflammatory vessel wall abnormalities	Disorders of collagen production and increased capillary fragility: scurvy, Ehlers–Danlos syndrome, solar purpura, steroid purpura, amyloidosis and trauma
Inflammatory vessel wall abnormalities or damage to the vessel wall by intravascular thrombi or emboli	Non-LCV vasculitis (e.g., lymphocytic vasculitis) Disseminated intravascular coagulation (DIC) Thrombotic thrombocytopenic purpura (PTI) Emboli: cardiac myxoma, cholesterol emboli, septic and infectious emboli Pigmented purpuric dermatosis Gardner–Diamond syndrome
Coagulation, platelet and other intravascular abnormalities	Platelet dysfunction disorders (e.g., Von Willebrand disease, Glanzmann disease, Wiskott–Aldrich syndrome, Bernard–Soulier syndrome) Thrombocytopenia Clotting factor defects