Table 1.
Patient baseline demographic and clinical characteristics for MSA and LF
| Measure | MSA N = 465 |
LF N = 166 |
p value |
|---|---|---|---|
| Age, years (mean ± SD) | 46.6 ± 13.6 | 56.3 ± 12.6 | < 0.0001 |
| Gender, % of patients | 0.866 | ||
| Male | 63.7% | 49.4% | |
| Female | 36.3% | 50.6% | |
| BMI (kg/m2) (mean ± SD) | 25.7 ± 3.7 | 27.81 ± 4.0 | < 0.0001 |
| Years with GERD (mean ± SD) | 9.0 ± 7.7 | 9.2 ± 8.6 | 0.7950 |
| Years of PPI Use (mean ± SD) | 6.1 ± 5.3 | 5.7 ± 6.0 | 0.5184 |
| Esophagitis, % of patients | 0.0130 | ||
| None | 53.0% | 40.9% | |
| Grade A | 31.7% | 29.6% | |
| Grade B | 13.5% | 16.4% | |
| Grade C | 1.1% | 8.2% | |
| Grade D | 0.7% | 5.0% | |
| Barrett’s Esophagus, % of patients | 1.7% | 12.7% | < 0.0001 |
| Hiatal Hernia Size, % of patients | < 0.0001 | ||
| None | 19.7% | 7.5% | |
| 1–3 cm | 78.9% | 44.4% | |
| > 3 cm | 1.4% | 48.1% | |
| Total % Time pH < 4 (mean ± SD) | 12.2 ± 11.4 | 13.0 ± 14.7 | 0.5830 |
| Moderate GERD, % of patientsa | 90.8 | 18.1 | |
| Severe GERD, % of patientsb | 9.2 | 81.9 |
BMI body mass index, GERD gastroesophageal reflux disease, LF laparoscopic fundoplication, MSA magnetic sphincter augmentation, PPI proton pump inhibitor
aModerate GERD defined as hiatal hernia ≤ 3 cm, no Barrett’s esophagus, no motility disorder, and esophagitis ≤ Grade B by LA Classification
bSevere GERD defined as one or more of: hiatal hernia > 3 cm, Barrett’s esophagus, motility disorder and/or Grade C or D esophagitis by LA Classification