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. 2021 Jan 13;70(7):2087–2093. doi: 10.1007/s00262-020-02832-0

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Representative photos, CT scans and immunohistochemistry of patient 3. a Hematoxylin and eosin (H&E) staining as well as immunochemistry for MCPyV and PD-L1 (clone 22–8) of tissue obtained prior to initiating IPI/NIVO after progression upon chemotherapy (cutaneous metastasis, right thigh). b Clinical presentation before initiating IPI/NIVO and after 4 cycles of IPI/NIVO (right thigh). c CT scans before IPI/NIVO and after 4 cycles of IPI/NIVO showing a partial remission of a parailiacal lymph node metastasis