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. Author manuscript; available in PMC: 2022 Jun 1.
Published in final edited form as: Alzheimers Dement. 2021 Jan 21;17(6):1005–1016. doi: 10.1002/alz.12259

Figure 5.

Figure 5.

Strongest predictors of mutation carrier (MC) status for autosomal dominant Alzheimer’s disease (ADAD) as identified by Relief algorithms. The strongest predictors across all modalities were the precuneus, caudate, and anterior cingulate. Changes in amyloid PET (PiB, blue circle) were primarily seen within subcortical regions. Changes in metabolism (FDG, orange circle) showed more cortical involvement. Volumetric changes (Volume, green circle) showed both cortical and subcortical involvement.