Table 1.
Treatment | Symptom response | EGD outcome (EREFS) | Eosinophil counts, proximal (eos/hpf) | Eosinophil counts, distal (eos/hpf) | Month of biopsy | Additional Notes |
---|---|---|---|---|---|---|
Omeprazole 20 mg twice daily x 12 weeks | No | Ex2, R1, E1, F1, S0 No dilation |
62 | 21 | March | |
2FED* (dairy, wheat) x 8 weeks | No | Ex1, R2, E2, F1, S11 No dilation |
90 | 45 | August | |
4FED (dairy, wheat, egg, soy) x 6 weeks | No | Ex1, R2, E1, F1, S9 Dilation (Savary to 11mm) |
180 | 10 | October | |
6FED (dairy, wheat, egg, soy, peanuts/tree nuts, fish/shellfish) x 6 weeks | No | Ex1, R2, E1, F1, S9 Dilation (Savary to 12mm) |
140 | 60 | November | |
Oral viscous budesonide (OVB) 1 mg twice daily x 8 weeks | yes | Ex0, R1, E0, F0, S16 Dilation (Savary to 17mm) |
0 | 0 | March | OVB subsequently stopped due to family preference in order to start SCIT and observe the response |
Off OVB and on multiallergen SCIT (build-up phase) x 3 months | yes | Ex1, R1, E1, F1, S16 Dilation (Savary to 17mm) |
0 | 48 | August | |
Multiallergen SCIT (maintenance phase) x 3 months | yes | Ex1, R0, E0, F1, S0 | 0 | 5 | March | |
Multiallergen SCIT (maintenance phase) x 8 months | yes | Ex0, R0, E0, F0, S0 | 0 | 2 | August | Remains asymptomatic on 18+ months of maintenance SCIT; follow-up EGD deferred due to covid-19 pandemic |