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. 2021 Mar 31;133(11-12):602–609. doi: 10.1007/s00508-021-01832-z

Table 2.

Changes in the microarchitecture of syphilitic skull bone

ID Sex Age (years) Cortical
porosity
Cortical
thinning
Cortical
loss
Sclerotic
reorganization
Perforation
1 M 27 + + Y
2 M 40 ++ ++ +++ ++ Y
3 M 40 + + + Y
4 M 42 + +++ Y
5 M 43 ++ ++ +++ +++ Y
6 M 43 +++ +++ ++ + Y
7 M 48 + + Y
8 M 52 +++ + ++ ++ Y
9 M 56 + ++ + Y
10 M 66 +++ ++ + Y
11 F 27 + ++ ++ Y
12 F 29 ++ + ++ + Y
13 F 31 ++ + + +++ Y
14 F 35 +++ ++ + ++ Y
15 F 53 ++ +++ ++ + Y
16 F 54 ++ ++ Y
17 F 58 +++ +++ + + Y
18 F 64 +++ +++ + Y
19 F 65 ++ ++ ++ +++ Y
20 F 65 +++ ++ ++ + Y
Percentage of frequency [%] 100 75 80 80 100

+, ++, +++ semi-quantitative gradation of cortical porosity, cortical thinning, cortical loss and sclerotic reorganization by one single observer; Y yes. Frequency is calculated by including all graduations (+,++,+++)