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. 2021 Apr 14;36(7):1487–1498. doi: 10.1007/s00384-021-03926-6

Fig. 3.

Fig. 3

Trend analysis of the twelve patients who underwent resection of their initial primary colorectal cancer (PCRC) as well as for their metachronous colorectal cancer (MCRC) years later at our institution. Every line that illustrates more than just one patient is provided with the respective numbers of patients in this group. A relationship was identified neither for the TNM classification nor for the tumor grading. Regarding the M1-PCRC shown in the left lower panel, one patient with a primary carcinoma of the sigmoid and liver metastasis underwent combined resection (R0) but developed metachronous cancer of the ascending colon with a limited carcinomatosis peritonei 4 years later. He was alive without recurrence 2 years after the last operation