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. 2021 Jun 11;11:12375. doi: 10.1038/s41598-021-91649-7

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Relationship between the mRNA expression of CBXs and individual cancer stages of GC patients. The mRNA expression levels of 8 CBXs were remarkably related to individual cancer stages, and patients who were in more advanced stages tended to exhibit higher mRNA expression levels of CBXs. The mRNA expression levels of CBX1/3, CBX2/5, and CBX4/6 were the highest in stage 3 (A,C), stage 4 (B,E), and stage 2 (D,F), respectively. However, the mRNA expression levels of CBX7/8 were the highest in stage 1 (G,H). *P ˂ 0.05, **P ˂ 0.01, ***P ˂ 0.001.