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. 2021 Jun 11;11:12350. doi: 10.1038/s41598-021-91726-x

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Mean grouping coefficient in dendrites with and without tau pathology. (A) Mean grouping coefficient in each single SomaTau + (n = 6; red) and SomaTau- (n = 5; green) dendrite. Boxplots with the mean grouping coefficients in the SomaTau- and SomaTau + dendrites. (B) The permutation analyses show a higher mean grouping coefficient in the Tau + compared to the Tau- group (p < 0.001). In all boxplots, their bottom and the top edges denote the 25th and 75th percentiles of the data, respectively. The whiskers extend to the largest and smallest data points. The results are similar after excluding the outliers.