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. 2021 Jun 11;11:12350. doi: 10.1038/s41598-021-91726-x

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Changes in the mean grouping coefficient after random attacks of spines in healthy dendrites. Illustration of attacks on random spines in a representative dendrite in groups of (A) 1, (D) 3 and (G) 5. (B,E,H) Percentage increases in the mean grouping coefficient (GC) in that dendrite as a function of the number of removed spines in the three cases respectively. Mean grouping coefficient of the attacked vs. healthy dendrites after the removal of 150 spines in groups of (C) 1, (F) 3 and (I) 5. The grey line shows the theoretical line of no change in the grouping coefficient, while the black line is the line that best fits the observed data after the attacks. This figure shows results for dendrite no. 2; the complete set of results for each SomaTau- dendrite are shown in Supplementary Table S5. Means and standard deviations are computed over 100 random attacks.