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. 2021 Jun 11;12(6):608. doi: 10.1038/s41419-021-03887-2

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — A TRAF2 knockdown affects EGFR protein level. DYRK1A and TRAF2 were silenced by shRNAs in U251 cells and cell lysates probed with EGFR, DYRK1A, and TRAF2 antibodies. B EGFR protein levels were analyzed in A172 cells after shRNA-mediated knockdown as in A. C DYRK1A knockdown causes that TRAF2 overexpression does not rescue EGFR protein level in TRAF2-silenced cells. U251 cells, silenced alone with TRAF2 shRNA or co-silenced with TRAF2 and DYRK1A shRNA were transfected with Myc-TRAF2, and protein level of EGFR analyzed. D Same as in C but A172 cell line was used.