Table 5.
Prevalence of adverse effects in percentage.
| M3 | M6 | M12 | M24 | |
|---|---|---|---|---|
| Skin nodules | 52.9 | 54.9 | 61.4 | 57.4 |
| Confusion | 5.8 | 2.8 | 2.9 | 2.9 |
| Hallucinations | 18.6 | 19.4 | 27.1 | 37.5 |
| ICDa | ||||
| Mild | 23.1 | 13.8 | 17.9 | 8.6 |
| Moderate | 6.2 | 7.7 | 7.5 | 10.3 |
| Marked | 6.2 | 1.5 | 3.0 | 3.4 |
| Severe | 0 | 0 | 0 | 0 |
| Sedation/Drowsiness | 33.3 | 30.6 | 30.0 | 26.5 |
| Insomnia | 14.5 | 18.1 | 21.4 | 11.8 |
| Nausea | 30.4 | 23.6 | 20.0 | 11.8 |
| Orthostatic hypotension | 23.2 | 22.9 | 24.3 | 31.3 |
Values are in percentage (%).
aImpulse control disorders (ICDs) such as hypersexuality, compulsive eating, compulsive shopping, pathological gambling, punding, and hobbyism. Severity of ICDs was rated according to ASBPD-4 (4 = severe disorder; 3 = marked disorder; 2 = moderate disorder; 1 = mild disorder; 0 = absence of disorder).