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. 2021 Jun 11;11:12358. doi: 10.1038/s41598-021-91661-x

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Network-based potential roles of (non)identified proteins in platelet proteome in arterial thrombosis and hemostasis. Using a published meta-analysis of mouse genes in thrombosis and bleeding, the network was built in Cytoscape, containing 267 core genes (bait nodes), 2679 new nodes, connected by 19.7 k interactions¹⁵. (A) Redrawn network visualization with color-coded proteins identified (green) or not identified (red) in the platelet proteome, with relevant transcript levels (node size, log2fpkm). Names are listed of 40 proteins with highest mRNA expression levels. (B) Distribution profile of (non)identified proteins with transcript levels (median copy numbers, median log2pkm). No mRNA = below relevant threshold. Attribute lists are given in Suppl. Datafile 4.