Table 2.
Parameters of GRN model for layer formation
| Commitment probabilities | C M | C 6 | C 5 | C 4 | C 3 | C 2 |
|---|---|---|---|---|---|---|
| Human temporal cortex | 0.16 | 0.1 | 0.2 | 0.3 | 0.5 | 0.7 |
| Rat hindlimb somatosensory cortex | 0.08 | 0.2 | 0.2 | 0.3 | 0.5 | 0.6 |
| Mouse barrel cortex | 0.14 | 0.3 | 0.2 | 0.5 | 0.5 | 0.4 |
| Macaque visual cortex | 0.11 | 0.2 | 0.2 | 0.5 | 0.4 | 0.5 |
| Apoptosis probabilities and Timing threshold | P M | P 6 | P 5 | P 4 | P 3 | |
| Human temporal cortex | 0.7 | 0.65 | 0.55 | 0.5 | 0.3 | |
| Rat hindlimb somatosensory cortex | 0.55 | 0.6 | 0.7 | 0.5 | 0.5 | |
| Mouse barrel cortex | 0.45 | 0.6 | 0.5 | 0.4 | 0.5 | |
| Macaque visual cortex | 0.6 | 0.4 | 0.2 | 0.5 | 0.5 |
Notes: The parameters are listed, specifying the probabilities to commit to a specific neuron type (CM–C2, for MZ/layer 1 to layer 2) and the apoptotic probabilities at each stage (PM–P3, see Fig. 1). The final apoptotic probability P2 fulfills the criterion P2 + C2 = 1 and so is not listed as a model parameter