Table 1.
Average values for demographic, biomedical, and cognitive data at each measurement wave
| T3 (1998–2000) | T4 (2003–2005) | T5 (2008–2010) | T6 (2013–2014) | |
|---|---|---|---|---|
| Number of subjects | ||||
| S1 | 131 | 130 | 131 | 104 |
| S3 | 140 | 139 | 140 | 106 |
| S6 | – | – | 80 | 62 |
| Total | 271 | 269 | 351 | 272 |
| Background information, mean (SD) | ||||
| Education, years | 12.3 (4.2) | 12.3 (4.2) | 12.7 (4.1) | 12.9 (4.2) |
| Age, yearsa | 56 (8) | 62 (8) | 63 (13) | 65 (13) |
| No. women/men | 144/127 | 143/126 | 182/169 | 137/134 |
| Biomedical data, mean (SD) | ||||
| BMI (kg/m2) | 26.1 (3.7) | 26.4 (3.6) | 26.4 (3.8) | 26.5 (3.7) |
| Waist circumference (cm) | 89.5 (10.3) | 91.4 (9.9) | 92.1 (11.3) | 93.2 (10.9) |
| Diastolic blood pressure (mmHg) | 82.5 (9.7) | 83.5 (8.7) | 80.8 (9.2) | 80.6 (8.7) |
| Systolic blood pressure (mmHg) | 138.0 (19.3) | 139.6 (18.5) | 138.2 (18.8) | 138.9 (16.3) |
| Grip strength right (kg) | – | 38.1 (12.8) | 35.7 (12.4) | 36.2 (13.0) |
| Grip strength left (kg) | – | 42.5 (6.2) | 31.5 (10.8) | 35.8 (13.7) |
| Pulse (bpm) | 63.5 (8.6) | 62.0 (9.2) | 61.2 (9.0) | 61.3 (8.4) |
| Cognitive performance, mean (SD) | ||||
| Free recall | 10.1 (2.5) | 10.0 (2.36) | 9.6 (2.6) | 9.3 (3.1) |
| Fluency A | 13.1 (4.2) | 13.8 (4.7) | 12.3 (4.4) | 12.8 (4.8) |
| Letter Digit | 31.7 (6.4) | 31.3 (6.3) | 30.2 (7.7) | 29.1 (8.0) |
| Block design | 31.1 (9.4) | 30.2 (8.8) | 29.5 (9.7) | 28.6 (9.9) |
Note: Brain age predictions were calculated from image data at the T5 and T6 wave. S1, S3, and S6 are different study samples, recruited at T1 (1988–1991), T2 (1993–1995), and T5 (2008–2010), respectively.
aFor T3 and T4, mean and SD are calculated based on the stratified ages, while for T5 and T6, age at time of imaging is used.