Table 1.

Selected list of the databases of single nucleotide variants.

Variant Database	Database Description	Web Site	Reference
ClinVar	ClinVar aggregates information about genomic variation and its relationship to human health.	http://www.ncbi.nlm.nih.gov/clinvar (accessed on 1 May 2021)	[1]
COSMIC	Manually curated resource of somatic mutation of human cancers.	https://cancer.sanger.ac.uk/cosmic (accessed on 1 May 2021)	[19]
dbSNP	Database of human single nucleotide variations, microsatellites, and small insertions and deletions for both common variations and clinical mutations.	http://www.ncbi.nlm.nih.gov/snp (accessed on 1 May 2021)	[20]
UniProt humsvar	Lists of missense variants annotated in UniProtKB/Swiss-Prot human entries. The variant classification should not be considered for clinical and diagnostic use.	https://www.uniprot.org/docs/humsavar (accessed on 1 May 2021)	[21]
ICGC Data Portal	The ICGC Data Portal provides many tools for visualizing, querying, and downloading cancer data.	https://dcc.icgc.org/ (accessed on 1 May 2021)	[22]
OMIM	Online Catalog of Human Genes and Genetic Disorders.	http://www.omim.org (accessed on 1 May 2021)	[23]
GDC	The GDC Data Portal provides access to GDC harmonized data as well as an archive of legacy data from TCGA and other NCI programs.	https://portal.gdc.cancer.gov/ (accessed on 1 May 2021)	[24]