Figure 4.
DNA binding activity of C/EBPα and C/EBPβ transcription factors in astrocytes incubated with increasing doses of DHA (A) and EPA (B). After 24 h incubation with omega-3 PUFAs, cells were treated with 10 µg/mL IL-1β for 16 h. In nuclear fraction of these astrocytes, C/EBPα and C/EBPβ activity was determined colorimetrically. Indicators for statistical significance are common for both transcription factors. * p < 0.001 compared to unstimulated control cells; # p < 0.01, ## p < 0.001 compared to IL-1β- treated cells.