Figure 4.

Effect of C₆₀ administration on oxidative stress markers: ROS formation (a), O₂^•− (b), H₂O₂ (c), and TBARS (d) production in skeletal muscle mitochondria of 3-NPA-treated rats. Values are means ± SD (replicates=8). The data were analyzed for statistical significance using ANOVA followed by the Bonferroni post hoc test. (C)—control; (3NPA)—3-nitropropionic acid treated rats; (C₆₀ pre-T)—C₆₀ administration in pre-treatment regimen; (C₆₀ post-T)—C₆₀ administration in post-treatment regimen; (C₆₀)—C₆₀ administration alone. * p < 0.05 vs. control group; ^# p < 0.05 vs. 3-NPA treated rats.