Table 1.

Hemodynamic parameters measured 7 days after myocardial infarction via echocardiography.

	Sham	Sham + Empa	MI + Vehicle	MI + Empa
Heart rate (bpm)	413 ± 21	386 ± 14	401 ± 19	426 ± 34
EF (%)	59.9 ± 7.2	61.6 ± 4.5	53.0 ± 2.7	58.0 ± 5.1
GLS (%)	−24.1 ± 2.8	−23.5 ± 2.2	−16.6 ± 1.6 †††	−21.9 ± 3.2 *
FS (%)	16.0 ± 3.5	21.2 ± 1.6 †	15.3 ± 4.4	18.1 ± 3.2
SV (uL)	209.5 ± 22.8	274.8 ± 27.6 ††	216.4 ± 30.2	211.7 ± 31.5
CO (mL/min)	86.5 ± 10.2	105.8 ± 7.9 †	86.8 ± 13.3	90.6 ± 16
LVIDd (mm)	6.6 ± 0.3	7.3 ± 0.2	6.9 ± 0.5	6.9 ± 0.6
LVIDs (mm)	3.8 ± 0.6	3.8 ± 0.6	3.6 ± 0.7	3.7 ± 0.9
E/A Ratio	1.71 ± 0.24	1.58 ± 0.14	1.84 ± 0.31	1.69 ± 0.25
IVRT (mm/s)	0.05120 ± 0.00743	0.05123 ± 0.00508	0.05715 ± 0.00841	0.04585 ± 0.00810
IVCT (mm/s)	0.04754 ± 0.01319	0.04417 ± 0.01057	0.04616 ± 0.00893	0.03804 ± 0.00965

* P < 0.05 vs. vehicle treated animals; † p < 0.05 vs. sham, †† p < 0.01 vs. sham, ††† p < 0.001 vs. sham. Heart rate (bpm—beats per minute). EF—ejection fraction; GLS—global longitudinal strain; FS—fractional shortening; SV—stroke volume; CO—cardiac output; LVIDd—end-diastolic left ventricular internal diameter; LVIDs—end-systolic left ventricular internal diameter; E/A ratio—ratio of early to late mitral inflow diastolic velocities. IVRT—isovolumic relaxation time; IVCT—isovolumic contraction time (n = 6–8), mean ± SEM.