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. 2021 May 21;22(11):5443. doi: 10.3390/ijms22115443

Figure 9.

Figure 9

A33 does not affect basal motor coordination, but reduces the intoxicating properties of 2 g/kg alcohol in experimentally-naïve mice. Summary of the effects of pretreatment with either vehicle (VEH) or 1.0 mg/kg of A33 (1.0 A33; 30 min prior) on (A) the latency of B6NJ and B6J mice (3 females/3 males/group) to fall from a rotarod under an alcohol-free state and (B) following injection with 2 g/kg EtOH (~30 min post-alcohol). The data represent the mean ± SEM of the number of mice indicated, in addition to the individual data points for each experimental group. * p < 0.05 vs. VEH (main effect).