Table 1.

Sampling results Ca²⁺ permeability energetics.

Energy/Model (kcal. Mol−1)	α7	A-Dup	AB-Dup	AC-Dup	ABC-Dup	ACD-Dup	4-Dup	5-Dup
EC -> TM (around-1.5 nm)	−37.5	−37.5	−15.7	−23.6	−16.4	−21.6	−15.9	−13.9
Transmembrane domain (around 0 nm)	0.2	1.8	14.6	7.7	4.1	2.3	4.8	9.84
TM –> IC (around 2 nm)	−0.1	−12.5	−0.1	−10.4	1.1	−7.6	−6.6	−12.6
Exiting IC (around 6 nm)	51.1	37.6	81.2	52.3	63.1	43.7	52.8	37.3