Table 4.
Calculated organ radiation-dose estimates of 111In-DOTA-EB-cRGDfK for humans.
| Organ | Estimated Dose (mSv/MBq) |
|---|---|
| Brain | 0.026 |
| Breasts | 0.051 |
| Gallbladder Wall | 0.150 |
| LLI Wall | 0.622 |
| Small Intestine | 0.207 |
| Stomach Wall | 0.110 |
| ULI Wall | 0.376 |
| Heart Wall | 0.102 |
| Kidneys | 0.214 |
| Liver | 0.187 |
| Lungs | 0.096 |
| Muscle | 0.076 |
| Ovaries | 0.202 |
| Pancreas | 0.117 |
| Red Marrow | 0.080 |
| Osteogenic Cells | 0.176 |
| Skin | 0.043 |
| Spleen | 0.186 |
| Thymus | 0.070 |
| Thyroid | 0.057 |
| Urinary Bladder Wall | 0.195 |
| Uterus | 0.139 |
| Total Body | 0.086 |
| Effective Dose | 0.201 |
Dosimetry was analyzed by the OLINDA/EXM software. Extrapolated radiation dose for a 70-kg female adult. LLI, Lower large intestine; ULI, upper large intestine.