Figure 5.

RAD51 is involved in the regulation of autophagy-associated genes in HepG2 and MCF7 cell lines. (a) Snapshots of ChIP-seq browser tracks for the ATG3 and ATG5 genes are shown. (b) Transcript levels of RAD51 were assessed in HepG2 and MCF-7 cells treated with B02 or RS-1 at different concentrations for 24 h. (c) Transcript levels of ATG3 and ATG5 were assessed in HepG2 and MCF7 cells treated with B02 (left) or RS-1 (right) at different concentrations for 24 h. TBP was used for the normalization of each cell line level. * p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001. The analysis was performed using one-way ANOVA. Data are shown as mean ± SEM.