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. 2021 May 22;26(11):3100. doi: 10.3390/molecules26113100

Scheme 16.

Scheme 16

Synthetic scheme for preparation of hybrids 6870. Reaction conditions: (a) sodium ascorbate, CuSO4·5H2O, t-BuOH/THF/H2O (3:1:1); (68: 63% yield; 69: 49% yield; 70: 68% yield).