Scheme 18.
Synthesis of the triazole-linked morpholino dinucleotide. Reaction conditions: (a) CuI, THF:t-BuOH:H2O (3:2:1), μW, 80 °C, 1 h; (b) EtN(i-Pr)2, ClP(OCH2CH2CN)N(i-Pr)2, DMAP, THF, r.t.
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