Table 2.
Associations between antenatal characteristics and patient demographics with occurrence of AKI.
| Prenatal characteristics | No AKI (n = 56) | AKI (n = 34) | p value |
|---|---|---|---|
| Left-sided CDH, n (%) | 47 (83.9) | 27 (79.4) | 0.80 |
| Percent predicted lung volume, mean (SD) | 25.71 (8.00) | 17.45 (7.34) | <0.001 |
| Total lung volume (mL), median [IQR] | 31.00 [26.75, 41.00] | 25.00 [21.00, 32.50] | <0.05 |
| Lung-to-head ratio, median [IQR] | 1.40 [1.10, 1.60] | 1.00 [0.80, 1.10] | <0.001 |
| Observed to expected lung-to-head ratio, median [IQR] | 52.00 [39.75, 66.00] | 38.50 [24.90, 48.00] | <0.01 |
| Liver up, n (%) | 29 (51.8) | 29 (85.3) | <0.01 |
| Patient demographics | No AKI (n = 56) | AKI (n = 34) | p value |
|---|---|---|---|
| GA (week), median [IQR] | 38.00 [36.00, 38.00] | 38.00 [36.00, 39.00] | 0.41 |
| Birth weight (kg), median [IQR] | 2.95 [2.50, 3.28] | 2.79 [2.50, 3.04] | 0.38 |
| Male gender, n (%) | 31 (55.4) | 19 (55.9) | >0.99 |
| Congenital heart disease, n (%) | 2 (3.6) | 5 (14.7) | 0.13 |
| Chromosomal anomaly, n (%) | 2 (3.6) | 3 (8.8) | 0.56 |
| Congenital anomaly of the kidney or urinary tract, n (%) | 3 (5.4) | 2 (5.9) | >0.99 |
| Outborn, n (%) | 31 (55.4) | 14 (41.2) | 0.28 |
| ECLS use, n (%) | 6 (10.7) | 26 (76.5) | <0.001 |
AKI acute kidney injury, CDH congenital diaphragmatic hernia, GA gestational age, ECLS extracorporeal life support.