Table 1.

Overview of chemical exposure in the four datasets. While most animals in the dataset ‘Fentanyl subcutaneous’ were exposed to Fentanyl subcutanenously, 6 animals were exposed intraveneously.

Exposure	Total nr of Animals	Nr of Placebo	Dosage	Vehicle/Volume
Fentanyl intravenous	26	6	0–16 mg/kg	PBS/1 mL/kg
Fentanyl subcutaneous	45	6	0–32 mg/kg	PBS/1 mL/kg
VX percutaneous (1)	32	0	1 mg/kg	IPA/16 µL/kg
VX percutaneous (2)	32	0	2 mg/kg	Neat/1 µL