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. 2021 May 22;26(11):3103. doi: 10.3390/molecules26113103

Table 1.

In vitro cytotoxic results of the target compounds 513, 16 and etoposide towards PC-3, NCI-H460 and Hela cell lines.

Compound No. In Vitro Cytotoxicity IC50 (μM) ± SD
PC-3 NCI-H460 Hela
5 29.31 ± 0.91 27.54 ± 0.43 25.73 ± 1.62
6 22.73 ± 1.40 21.12 ± 1.31 19.31 ± 0.45
7 17.50 ± 0.35 15.42 ± 0.32 14.62 ± 0.52
8 28.62 ± 1.15 26.92 ± 0.32 26.31 ± 0.46
9 35.12 ± 0.26 32.81 ± 0.51 31.05 ± 0.87
10 48.29 ± 0.36 47.12 ± 1.08 45.62 ± 1.34
11 59.13 ± 1.12 58.64 ± 1.41 58.12 ± 0.41
12 49.08 ± 0.92 48.13 ± 0.52 47.13 ± 0.95
13 56.71 ± 0.87 55.03 ± 0.61 53.76 ± 1.67
16 65.41 ± 0.75 61.05 ± 0.75 59.24 ± 1.20
Etoposide 17.15 ± 0.24 14.28 ± 0.15 13.34 ± 0.23