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. 2021 May 24;10(11):2259. doi: 10.3390/jcm10112259

Figure 5.

Figure 5

QRT-PCR shows a strong downregulation of miRNAs of the miR-506–514 cluster and miR-1299. Analysis of miR-508-3p, miR-509-3p, miR-514a-3p, and miR-1299 expression in normal human epidermal melanocytes (NHEM), melanoblast-related cells (MBrC), and at least 6 different melanoma cell lines (MM) via qRT-PCR. Bars represent mean + SEM, statistical significance was calculated using one-way ANOVA and subsequent Tukey’s Multiple Comparison Test with ΔCP values before normalization to NHEM and is indicated as * p ≤ 0.05 and *** p ≤ 0.001.