Table 7.
Dosage Form | Drug | Ingredients | Use/effect of Jojoba Oil | Ref. |
---|---|---|---|---|
Microemulsion | Antioxidant lycopene | Jojoba oil, alcohols, nonionic surfactant (Brij 96V) | To solubilize lycopene | [51] |
Microemulsion | - | Jojoba oil, alcohols, different nonionic surfactants, namely Brij 96V and Tweens, and water | To study the effect of Jojoba oil content on the type of the microemulsion | [52] |
Sub-micron emulsion | Diclofenac (Diethyl ammonium) | Jojoba oil, purified egg lecithin, Cremophor EL surfactant, and water | To increase the anti-inflammatory effect of topical preparations of diclofenac | [53] |
Gellified emulsion | Anti-acne agent, Benzoyl peroxide | Lipophilic surfactant (Span 60), jojoba oil, hydrophilic surfactant (Tween 20), propylene glycol, methyl paraben, propyl paraben, disodium EDTA, butylated hydroxy toluene, Carbopol 940, and water | To decrease the skin irritation and dryness caused by benzoyl peroxide | [54] |
Microemulsion | Methotrexate | Jojoba oil, Tween 80, Span-85 and water | Treatment of psoriasis vulgaris. | [55] |
Microemulsion | Synthetic retinoid tazarotene | Jojoba wax, labrasol/plurol isostearique and water | Treatment of psoriasis and increase in skin deposition of tazarotene | [56] |
Solid lipid nanoparticles | Valacyclovir hydrochloride |
Glyceryl monostearate. jojoba oil, polyethylene Glycol 400, Tween 80, and water | To benefit from jojoba oil moisturizing and stabilizing activity in the treatment of viral infections in humans | [57] |
Nanostructured lipid carriers | - | Glyceryl behenate, jojoba oil, Tween 80, cetrimide, glycerine, Carbopol 934 or Carbopol 980, triethanolamine, and water | To improve symptoms of some skin disorders like eczema | [58] |
Emulgels | Clotrimazole | Jojoba oil, hydroxypropyl methylcellulose (HPMC) Carbopol 934, Span 60, Brij 35, triethanolamine, propylene glycol, and water | An excipient for different topical antifungal preparations | [59] |
Hydrophobically modified co-polymers of acrylic acid, namely Pemulen TR1 and TR2, jojoba oil, and water | [60] | |||
Cutina lipogels | Fluconazole | Cutina, Jojoba oil | An excipient for fluconazole topical drug delivery | [61] |
Microemulsion gel | Jojoba oil, Brij 96, Capmul and, water | |||
Straightening emulsions | - | Jojoba oil, ammonium thioglycolate, self-emulsifying wax, oleth-3, mineral oil, propylene glycol, aqua, and preservative blend | As a conditioning agent added to the emulsion | [62] |
Skin non-penetrating sunscreens | - | Jojoba oil, methoxycinnamate | To link UV sunscreen molecules as methoxycinnamate to jojoba oil to form new filters | [63,64] |
Transdermal patch | Olanzapine | Jojoba oil, Eudragit polymer | As a penetration enhancer in transdermal delivery | [65] |
Small-sized agarose microcapsules | Bacillus Calmette–Guérin (BCG) vaccine | Agarose, jojoba oil | An excipient | [66,67] |
Small-diameter alginate beads | Calcium alginate matrix, jojoba oil | |||
Nanocapsules | Jojoba oil, Poly(€-caprolactone) Tween 80, and Span 60 | To study physical stability and the hemocompatibility of jojoba oil-based nanocapsules for parenteral administration | [68] | |
Solid nanoemulsion | Imiquimod, a Toll-like receptor 7 (TLR7) agonist + SIINFEKL antigen | Jojoba oil, sucrose fatty ester S-1670 and water | An excipient | [69] |
O/W microemulsions | Paclitaxel | Jojoba oil, d-α-tocopherol polyethylene glycol 1000 succinate (TPGS-1000), isobutanol, and water | As an excipient to load paclitaxel for cancer treatment | [70] |
Charged micelles | Small interfering RNAs (siRNAs) | Cationic lipids Bolaamphiphiles (GLH-58 and GLH-60) synthesized from jojoba oil | Starting material for the synthesis of lipids | [71] |