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. 2021 May 24;13(11):1711. doi: 10.3390/polym13111711

Table 7.

A summary of pharmaceutical dosage forms containing jojoba oil.

Dosage Form Drug Ingredients Use/effect of Jojoba Oil Ref.
Microemulsion Antioxidant lycopene Jojoba oil, alcohols, nonionic surfactant (Brij 96V) To solubilize lycopene [51]
Microemulsion - Jojoba oil, alcohols, different nonionic surfactants, namely Brij 96V and Tweens, and water To study the effect of Jojoba oil content on the type of the microemulsion [52]
Sub-micron emulsion Diclofenac (Diethyl ammonium) Jojoba oil, purified egg lecithin, Cremophor EL surfactant, and water To increase the anti-inflammatory effect of topical preparations of diclofenac [53]
Gellified emulsion Anti-acne agent, Benzoyl peroxide Lipophilic surfactant (Span 60), jojoba oil, hydrophilic surfactant (Tween 20), propylene glycol, methyl paraben, propyl paraben, disodium EDTA, butylated hydroxy toluene, Carbopol 940, and water To decrease the skin irritation and dryness caused by benzoyl peroxide [54]
Microemulsion Methotrexate Jojoba oil, Tween 80, Span-85 and water Treatment of psoriasis vulgaris. [55]
Microemulsion Synthetic retinoid tazarotene Jojoba wax, labrasol/plurol isostearique and water Treatment of psoriasis and increase in skin deposition of tazarotene [56]
Solid lipid nanoparticles Valacyclovir
hydrochloride
Glyceryl monostearate. jojoba oil, polyethylene Glycol 400, Tween 80, and water To benefit from jojoba oil moisturizing and stabilizing activity in the treatment of viral infections in humans [57]
Nanostructured lipid carriers - Glyceryl behenate, jojoba oil, Tween 80, cetrimide, glycerine, Carbopol 934 or Carbopol 980, triethanolamine, and water To improve symptoms of some skin disorders like eczema [58]
Emulgels Clotrimazole Jojoba oil, hydroxypropyl methylcellulose (HPMC) Carbopol 934, Span 60, Brij 35, triethanolamine, propylene glycol, and water An excipient for different topical antifungal preparations [59]
Hydrophobically modified co-polymers of acrylic acid, namely Pemulen TR1 and TR2, jojoba oil, and water [60]
Cutina lipogels Fluconazole Cutina, Jojoba oil An excipient for fluconazole topical drug delivery [61]
Microemulsion gel Jojoba oil, Brij 96, Capmul and, water
Straightening emulsions - Jojoba oil, ammonium thioglycolate, self-emulsifying wax, oleth-3, mineral oil, propylene glycol, aqua, and preservative blend As a conditioning agent added to the emulsion [62]
Skin non-penetrating sunscreens - Jojoba oil, methoxycinnamate To link UV sunscreen molecules as methoxycinnamate to jojoba oil to form new filters [63,64]
Transdermal patch Olanzapine Jojoba oil, Eudragit polymer As a penetration enhancer in transdermal delivery [65]
Small-sized agarose microcapsules Bacillus Calmette–Guérin (BCG) vaccine Agarose, jojoba oil An excipient [66,67]
Small-diameter alginate beads Calcium alginate matrix, jojoba oil
Nanocapsules Jojoba oil, Poly(€-caprolactone) Tween 80, and Span 60 To study physical stability and the hemocompatibility of jojoba oil-based nanocapsules for parenteral administration [68]
Solid nanoemulsion Imiquimod, a Toll-like receptor 7 (TLR7) agonist + SIINFEKL antigen Jojoba oil, sucrose fatty ester S-1670 and water An excipient [69]
O/W microemulsions Paclitaxel Jojoba oil, d-α-tocopherol polyethylene glycol 1000 succinate (TPGS-1000), isobutanol, and water As an excipient to load paclitaxel for cancer treatment [70]
Charged micelles Small interfering RNAs (siRNAs) Cationic lipids Bolaamphiphiles (GLH-58 and GLH-60) synthesized from jojoba oil Starting material for the synthesis of lipids [71]