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Trans-interaction of synaptic organizers (A). Neurexins and type IIa RPTPs are depicted as representative presynaptic adhesion molecules. Red arrows show the interactions where HS is involved. Asterisks indicate genetic association with neuropsychiatric disorders [66]. HSPGs are indicated by underlines (B). Trans-interactions of synapse organizers involving HSPGs are shown. HSPGs are indicated by underlines.
