Table 1.
Demographic information and ocular status of the 361 patients before phacoemulsification.
| Parameter | Total | Chi-Squared Test p Value + |
Group A | Group B | Group C | One-Way ANOVA p Value |
|---|---|---|---|---|---|---|
| Participant number | 352 | 29 | 71 | 252 | ||
| Age (year) | ||||||
| Mean ± SD | 69.0 ± 9.9 | 0.003 * | 68.9 ± 10.0 | 69.6 ± 10.1 | 68.9 ± 9.9 | 0.841 |
| Range | 41–90 | 48–86 | 46–87 | 41–90 | N/A | |
| Gender | 0.661 | |||||
| Male | 143 (40.6%) | 9 (31.0%) | 26 (36.6%) | 108 (42.9%) | 0.352 | |
| Female | 209 | 20 | 45 | 114 | N/A | |
| Eye | 0.416 | |||||
| Right | 181 (51.4%) | 17 (58.1%) | 39 (54.9%) | 125 (49.6%) | 0.528 | |
| Left | 169 | 11 | 31 | 127 | N/A | |
| Bilateral | 2 | 1 | 1 | 0 | ||
| Preoperative IOP (mmHg) | ||||||
| Mean ± SD | 15.0 ± 4.0 | 0.365 | 15.4 ± 4.2 | 14.6 ± 3.3 | 15.0 ± 4.1 | 0.570 |
| Preoperative VA | ||||||
| Mean logMAR ± SD | 1.05 ± 0.47 | 0.048 * | 0.93 ± 0.33 | 1.05 ± 0.45 | 1.05 ± 0.49 | 0.412 |
| Cataract grade (%) | 0.005 * | 0.198 | ||||
| I | 4 (1.1%) | 0 | 1 (1.4%) | 3 (1.2%) | ||
| II | 320 (90.9%) | 29 (100%) | 61 (85.9%) | 230 (91.3%) | ||
| III | 28 (8.0%) | 0 | 9 (12.7%) | 19 (7.5%) | ||
| ACD (mm) | 2.78 ± 0.29 | 0.160 | 2.76 ± 0.38 | 2.81 ± 0.23 | 2.77 ± 0.30 | 0.551 |
| Comorbidities | ||||||
| Glaucoma | 12 (3.4%) | 0.766 | 0 (0%) | 3 (4.2%) | 9 (3.6%) | 0.555 |
| Corneal dystrophy | 32 (9.1%) | 0.182 | 24(82.1%) | 4 (5.6%) | 4 (1.6%) | <0.001 * |
| Hypertension | 133 (37.8%) | 0.326 | 11 (36.7%) | 27 (38.0%) | 95 (37.7%) | 0.999 |
| Diabetes mellitus | 107(30.4%) | 0.923 | 12 (40.0%) | 23 (32.4%) | 72 (28.6%) | 0.338 |
| Preoperative HCEC status | ||||||
| Cell density ± SD(cell/mm2) | 2268.7 ± 679.5 | <0.001 * | 814.2 ± 119.7 | 1512.0 ± 271.4 | 2646.1 ± 288.2 | <0.001 * |
| CV % | 34.2 ± 11.1 | 0.650 | 40.8 ± 13.9 | 36.4 ± 11.8 | 32.8 ± 10.2 | <0.001 * |
| HEX % | 63.8 ± 10.0 | 0.215 | 58.4 ± 14.6 | 60.3 ± 11.9 | 65.3 ± 8.1 | <0.001 * |
| CCT (μm) Mean ± SD | 553.3 ± 34.0 | 0.981 | 557.8 ± 35.7 | 557.6 ± 36.1 | 551.0 ± 33.7 | 0.269 |
Demographic data were collected and analyzed from all patients. * p-value < 0.05. + The chi-squared test was used to examine the association between factors and postoperative ECD change (%). ACD: anterior chamber depth; CV: coefficient of variation; CCT: central cornea thickness; IOP: intraocular pressure; HCEC: human corneal endothelial cells; HEX: hexagonality; logMAR: logarithm of the minimum angle of resolution. Group A: Patient preoperative endothelial cell density (ECD) below 1000 cells/mm2. Group B: Patient preoperative endothelial cell density (ECD) between 1000 and 2000 cells/mm2. Group C: Patient preoperative endothelial cell density (ECD) above 2000 cells/mm2.