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. 2021 May 24;10(11):2272. doi: 10.3390/jcm10112272

Table 1.

Characteristics of study participants among the muscle-to-fat mass ratio tertiles.

ALL
(n = 113)
Low MFR
(n = 28)
Medium MFR
(n = 57)
High MFR
(n = 28)
p-Value
Age, year 14.0 (13.0–15.0) 14.0 (12.3–15.8) 14.0 (13.0–15.0) 14.0 (13.0–15.0) 0.77
Height, cm 165.7 (158.4–171.8) 166.9 (157.6–170.3) 166.5 (157.9–173.2) 165.0 (158.9–170.0) 0.9
Weight, kg 55.7 (44.9–65.0) 68.7 (51.7–80.8) 56.8 (48.4–63.0) 48.1 (44.2–57.8) 0.0023
Body mass index, kg/m2 19.7 (17.9–22.4) 24.9 (19.5–28.0) 20.2 (18.0–22.0) 18.1 (16.6–19.3) <0.0001
Skeletal muscle mass, kg 26.6 ± 7.0 27.3 ± 8.2 26.7 ± 7.4 25.6 ± 4.4 0.44
Fat mass, kg 7.2 (4.9–11.0) 14.3 (10.2–23.4) 7.4 (5.8–9.4) 4.0 (3.1–5.1) <0.0001
Skeletal muscle mass/weight 0.48 (0.45–0.49) 0.43 (0.40–0.44) 0.48 (0.46–0.49) 0.51 (0.49–0.10) <0.0001
Fat mass/weight 0.14 (0.11–0.18) 0.22 (0.20–0.28) 0.14 (0.12–0.16) 0.08 (0.07–7.8) <0.0001
Skeletal muscle to fat mass ratio 3.39 (2.57–4.64) 1.94 (1.43–2.28) 3.39 (2.87–4.07) 6.38 (5.11–7.42) <0.0001
Hand grip, kg 32.8 ± 9.5 33.4 ± 10.8 32.8 ± 10.0 32.0 ± 7.1 0.68
Knee extension force, Nm/kg 2.26 ± 0.45 2.00 ± 0.38 2.32 ± 0.43 2.40 ± 0.47 0.0029
Knee flexion force, Nm/kg 1.07 (0.94–1.26) 1.00 (0.84–1.08) 1.13 (0.99–1.33) 1.10 (0.95–1.31) 0.0068
Squat jump, cm 27.0 ± 6.1 22.5 ± 5.1 28.2 ± 5.7 29.0 ± 5.4 <0.0001
Counter movement jump, cm 30.0 ± 6.0 25.6 ± 4.9 31.2 ± 5.7 32.3 ± 5.6 <0.0001
Aspartate aminotransferase, IU/L 23.0 (19.5–25.5) 24.0 (19.0–27.0) 22.0 (19.0–25.0) 23.5 (21.0–26.8) 0.34
Alanine aminotransferase, IU/L 17.0 (14.0–23.0) 22.0 (15.3–34.0) 17.0 (13.0–22.0) 15.0 (13.0–20.0) 0.0028
Gamma-glutamyl transferase, IU/L 15.0 (13.0–19.5) 16.5 (15.3–34.0) 15.0 (13.3–26.0) 15.5 (13.0–16.8) 0.16
Fasting blood glucose, mg/dL 98.0 (94.0–102.5) 99.0 (94.3–101.0) 97.0 (94.0–102.5) 97.0 (92.3–103.8) 0.85
Triglycerides, mg/dL 68.0 (45.0–82.5) 74.5 (45.3–130.0) 68.0 (46.0–82.5) 57.0 (43.8–71.3) 0.048
High-density lipoprotein cholesterol, mg/dL 63.9 ± 12.2 63.7 ± 13.1 63.8 ±12.1 63.9 ± 12.2 0.96
Obesity (body mass index > 25 kg/m2) 18 (15.9%) 13 (46.4%) 5 (8.8%) 0 (0.0%) <0.0001
Alanine aminotransferase (>26 IU/L) 16 (15.0%) 11 (39.3%) 4 (7.0%) 1 (3.6%) <0.0001

Results are presented as mean ± standard deviation, median (interquartile range), or number (LRB%). Low MFR: <25th percentile; medium MFR: 25th–75th percentile; high MFR: >75th percentile. Abbreviations: MFR, muscle-to-fat mass ratio; n, number.