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. 2021 May 24;22(11):5514. doi: 10.3390/ijms22115514
BCS Biopharmaceutical classification system
PC Phenolic compound
P-gp P-glycoprotein
SGLT1 Sodium-glucose transporter
Nrf-2 Nuclear factor (erythroid-derived 2)-like 2
LogP Partition coefficient logarithm P
RB Rotatable bonds
HBA/HBD Hydrogen-bonding acceptor/donor
FA Ferulic acid
FDA Food and Drug Administration
AUC Area under the curve
LogD Distribution coefficient logarithm D
QSAR Quantitative structure-activity relationship
RP-HPLC Reverse phase high-performance liquid chromatography
USFDA United States Food and Drug Administration
WHO World Health Organization
N/A Not available
S Solubility
API Active pharmaceutical ingredient
D Highest dose
D/S Highest dose and solubility ratio
EMA European Medicines Agency
IR Immediate release
EML List of Essential Medicines
SDAD Single dietary abundant dose
ADI Acceptable daily intake
NOAEL No observed adverse effect level