Skip to main content
. 2021 May 24;22(11):5526. doi: 10.3390/ijms22115526

Figure 4.

Figure 4

Analysis of double-stranded DNA breaks in neuron-like cells after 1 h incubation with glucose or insulin. (1) Sample microphotographs of a nuclear diffusion halo: A—control (untreated cells), B—glucose 50 mM, C—glucose 100 mM and D—glucose 150 mM. (2) Sample microphotographs of nuclear diffusion halo: A—control (untreated cells), B—insulin 50 µM, C—insulin 100 µM and D—insulin 150 µM. (3) A comparison of relative NDF for neuronal-like cells incubated for 1 h with glucose or insulin. Statistically significant differences compared to the untreated neuron-like cells: *** p < 0.001.