Skip to main content
. 2021 May 21;162(7):bqab102. doi: 10.1210/endocr/bqab102

Figure 1.

Figure 1.

Tafazzin deficiency reduces plasma insulin levels. Islets isolated from Tg and NTg mice were used to quantitate (A) total CL, (B) MLCL, and (C) the ratio of MLCL/CL by tandem mass spectrometry (n = 2-4). (D) Quantitation of individual CL species from isolated islets (n = 2-4). Plasma insulin levels following intraperitoneal glucose administration (2 g/mL) of Tg and NTg animals at (E) 4 months and (F) 10 months of age (n = 8-10). (G) Fasting plasma insulin levels. (H) The plasma insulin level at t = 10 minutes after glucose injection during GTT/plasma insulin level after 16 hours of fasting at t = 0 minutes (before glucose injection). Values are means ± SEMs. *P < 0.05 compared with NTg mice fed the same diet. #P < 0.05 compared with all other groups. CL, cardiolipin; MLCL, monolysocardiolipin; NTg, nontransgenic; Tg, transgenic.