Table 2.
Multivariable associations of baseline characteristics with plasma concentrations of TMAO.
| Variable | Std β (95% CI) | p Value |
|---|---|---|
| Men, (yes) | −0.17 (−0.36; 0.01) | 0.06 |
| Age, years | −0.04 (−0.13; 0.06) | 0.45 |
| BMI, kg/m2 | 0.00 (−0.08; 0.08) | 0.98 |
| SBP, mmHg | 0.27 (0.17; 0.38) | <0.001 |
| DBP, mmHg | −0.19 (−0.29; −0.09) | <0.001 |
| Never smoked, (yes) | −0.07 (−0.28; 0.13) | 0.47 |
| Diabetes duration, years | −0.05 (−0.13; 0.03) | 0.24 |
| Macrovascular comp., (yes) | 0.11 (−0.06; 0.28) | 0.22 |
| Microvascular comp., (yes) | 0.23 (0.06; 0.41) | 0.009 |
| Glucose, mg/dL | −0.04 (−0.13; 0.05) | 0.35 |
| HbA1c, % | −0.01 (−0.11; 0.08) | 0.75 |
| TC, mmol/L | 0.12 (0.02; 0.22) | 0.02 |
| HDL-C, mmol/L | −0.02 (−0.11; 0.07) | 0.69 |
| Triglycerides, mmol/L | −0.10 (−0.19; 0.00) | 0.05 |
| BCAA, μmol/L | 0.18 (0.09; 0.27) | <0.001 |
| Serum creatinine, mmol/L | 0.17 (0.09; 0.26) | <0.001 |
| Albuminuria, (yes) | −0.10 (−0.28; 0.08) | 0.28 |
Standardized regression coefficients are shown. Abbreviations: BCAA, Branched-chain amino acids; BMI, body mass index; DBP, diastolic blood pressure; HbA1c, glycated hemoglobin; HDL-C, high-density lipoprotein cholesterol; SBP, systolic blood pressure; TC, total cholesterol. p values <0.05 are highlighted with bold font.