| 5-HT | 5-hydroxytryptamine |
| cAMP | Cyclic adenosine 3, 5’-monophosphate |
| CGRP | calcitonin gene-related peptide |
| CNS | central nervous system |
| CSD | cortical spreading depression |
| DpMe | deep mesencephalic nucleus |
| DRN | dorsal raphe nuclei |
| DRN | dorsal raphe nuclei |
| DSM-5 | Diagnostic and Statistical Manual of Mental Disorders, 5th Edition |
| eVLPO | extended ventrolateral preoptic neurons in the hypothalamus |
| GABA | gamma-aminobutyric acid |
| ICD-10-CM | International Classification of Diseases, 10th Edition, Clinical Modification |
| ICHD-3 | International Classification of Headache Disorders |
| ICSD-3 | International Classification for Sleep Disorders, 3rd Edition |
| LC | aminergic locus coeruleus neurons |
| LC | locus coeruleus |
| LDT | interneurons of the lateral dorsal tegmental |
| LDT | lateral dorsal tegmental nuclei neurons |
| MnPO | median preoptic nucleus |
| NO | nitric oxide |
| NOS | nitric oxide synthase |
| NREM | non-rapid eye movement |
| OSA | obstructive sleep apnea |
| OX1R | hypocretin receptor 1 |
| OX2R | hypocretin receptor 2 |
| PACAP | pituitary adenylate cyclase-activating polypeptide |
| PB | parabrachial nucleus |
| PPT | pedunculopontine tegmental |
| PPT | pedunculopontine tegmental |
| PZ | parafacial zone |
| REM | rapid eye movement |
| RLS | rest leg syndrome |
| SLD | sublaterodorsal nucleus |
| TMN | tuberomammillary nucleus |
| VIP | vasoactive intestinal peptide |
| vlPAG | ventrolateral periaqueductal grey region |
| VLPO | ventrolateral preoptic neurons in the hypothalamus |
| VTA | ventrolateral tegmental nucleus |