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. 2021 May 24;13(11):1717. doi: 10.3390/polym13111717

Table 1.

Functional groups of chitosan chemical modification.

No Functional Groups Chemical Reaction
1 C2–NH2

  • Metal coordination

  • Chemical coupling

  • Chemical cross-link

  • Graft copolymer

  • Alkylation

  • Acylation

  • Shift Base
2 C3–OH

  • Sulfonation

  • Alkanoylation
3 C6–OH

  • Metal coordination

  • Chemical coupling

  • Chemical cross-link

  • Graft copolymer

  • Esterification

  • Carboxymethylation

  • Alkylation
4 Acetyl amino
5 Glycosidic bond Glycosidic bond cleavage degradation