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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: J Mammary Gland Biol Neoplasia. 2020 Nov 4;25(4):237–253. doi: 10.1007/s10911-020-09463-2

Figure 1. Considerations for preclinical modeling of obesity and breast cancer.

Figure 1.

Each factor, including the presence of estrogen, tumor subtype, rodent strain, immune function, housing temperature, and diet influences and/or is influenced by obesity. Representative images of Lean and Obese female rats (top; white) and mice (bottom; black) derived from these models are shown.