Table 1.
Diet numbers and composition used in mouse and rat obesity studies.
MOUSE | RAT | |||||||
---|---|---|---|---|---|---|---|---|
DIET | Low Fat Low Sugar (LFLS) | Low Fat High Sugar (LFHS) | High Fat High Sugar (HFHS) | High-Fat (HF) | ||||
Product # | D11092101 | D19043002 | D15031601 | D12344 | ||||
(Research Diets) | g % | kcal % | g % | kcal % | g % | kcal % | g % | kcal % |
Protein | 20.3 | 20.8 | 20.3 | 20.8 | 24.0 | 20.8 | 24.6 | 20.8 |
Carbohydrate | 66.0 | 67.7 | 66.0 | 67.7 | 45.2 | 39.2 | 39.7 | 33.1 |
Fat | 5.0 | 11.5 | 5.0 | 11.5 | 20.5 | 40.0 | 24.6 | 46.1 |
Total | 100.0 | 100.0 | 100.0 | 100.0 | ||||
kCal/gram | 3.90 | 3.90 | 4.61 | 4.80 | ||||
Ingredient | grams | kcal | grams | kcal | grams | kcal | grams | kcal |
Casein, Lactic | 200 | 800 | 200 | 800 | 200 | 800 | 200 | 800 |
DL-Methionine | 3 | 12 | 3 | 12 | 3 | 12 | 3 | 12 |
Corn Starch | 531 | 2124 | 278 | 1110 | - | - | 163 | 650 |
Maltodextrin | 119 | 476 | 80 | 320 | 80 | 320 | 150 | 600 |
Sucrose | - | - | 293 | 1170 | 293 | 1170 | - | - |
Cellulose BW200 | 50 | - | 50 | - | 50 | - | 50 | - |
Milk Fat (Butter) | 11 | 99 | 11 | 99 | 134 | 1209 | ||
Corn Oil | 39 | 351 | 39 | 351 | 39 | 351 | 200 | 1800 |
Minerals Mix S10001 | 35 | - | 35 | - | 35 | - | 35 | - |
Vitamin Mix V10001 | 10 | 40 | 10 | 40 | 10 | 40 | 10 | 40 |
Choline Bitartrate | 2 | - | 2 | - | 2 | - | 2 | - |
Cholesterol | - | - | - | - | - | - | - | - |
Total | 1000.0 | 3902.0 | 1000.0 | 3902.0 | 845.8 | 3902.1 | 812.5 | 3902.0 |
Bold values indicate key differences in the fat and sucrose content of the diets, as described in the text