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. 2021 May 25;14(11):2806. doi: 10.3390/ma14112806

Table 1.

Literature regarding species.

Source Source Organ Subject Type Peptide Sequence/Amino Acid Contents MW Biological Function
Bovine/calve/yak Calves blood extract [9] Rabbits Not given Not given Not given Bone regeneration
Bone and calcium citrate [10] Tail suspended ovariectomized rats I Not given Not given Increased serum osteocalcin levels
Yak bone [12] Ovariectomized rats I Not given Not given Bone formation biomarkers
Yak bones collagen [13] Not given I GPSGPAGKDGRIGQPG
GDRGETGPAGPAGPIGPV
<3 KDa Osteoblast proliferation
Bovine Achilles tendon [14] Not given I 44 peptides
GERGFPGLPGPS
29 peptides with <1 KDa Angiotensin-converting enzyme (ACE)-inhibitory activity
Bovine Achilles tendon [16] Not given I (1) Gly-Asp-Hyl-Gly-Glu-Thr-Gly-Glu-Gln-Gly-Asp-Arg,
(2) Phe-Leu-Pro-Gln-Pro-Pro-Gln-Glu-Lys-Ala-His-Asp-Gly-Gly-Arg
Several peptides <2 KDa Antimicrobial and radical scavenging
Bovine lung tissue [17] Not given Not clear Not given Not given anti-inflammatory
Bovine Nuchal ligament [15] Not given I Gly-Pro-Arg-Gly-Phe (not ACE inhibited)
Tyr-Trp and Leu-Arg-Tyr (ACE Inhibited)
Not given ACE inhibitor peptides
Porcine Porcine skin [18] Mouse lymphoma L5178YTK ±
(not a mouse)
Majorly IPeptides of ii, iii and iv Not given <K3Da Chronic wound healing
porcine leg bones [19] Osteoblast MC3T3-E1 cells (not a mouse) I Not given 1 to >5 KDa Overcome osteoporosis effects on bones
Fresh pig bone [20] Osteoblast MC3T3-E1 cells (not a mouse) I Not given Not given Upregulating osteoblasts
Pig skin gelatin water extracts [21] Male ICR mice Not given Not given <3 KDa Cure of cognitive
function
Porcine gelatin [22] Human Not given Not given 1200 Da language cognitive function and brain structure
Pig skin gelatin [23] Human neuroblastoma cell line (SH-SY5Y) Not given Not given >50 KDa Antioxidative and neuroprotective effect
Marine Pacific oyster (Crassostrea gigas) [24] SKH hairless mice (Mice dorsal skins) I Ile-Val-Val-Pro-Lys 554.72 Da Anti-photoaging
Fresh water Salmo Salar skin
Deep sea Tilapia Nilotica skin [25]
Rat Not given Asp, Glu, Ser, His, Gly, Thr, Arg, Ala, Tyr, Val, Met, Phe, Ile, Leu, Lys, Pro, Hyp 512.63 Da for Tilapia Nilotica Altering Cutaneous Microbiome
Colonization for wound healing
Redlip Croaker (Pseudosciaena polyactis) Scales [26] Not given I DGPEGR,
GPEGPMGLE, EGPFGPEG, YGPDGPTG, GFIGPTE, and IGPLGA
629.6, 885.9, 788.9, 762.7, 733.8, and 526.6 Da Anti-oxidation scavenging
Soft shell of turtle (Carapax Trionycis) [27] SD rats Not given Amino acid w.r.t mg/100 g Ser > Gly > Tyr > Ala > Glu > Asp > Cys > Val> Arg > Lys > Thr > Ile > Met > Leu > Try > His > Phe Not given Pre-biotic potential
Swim bladders of Atlantic cod (Gadus morhua) [28] Human fibro blast cell (MRC-5) I Not given ACS 182.9 ± 7.9
PSC
28.7 ± 1.7 KDa
High thermal properties
Mackerel fillets (Scomber scombrus) [29] Not given Not given Aspartic acid (Asp), Serine (Ser), Glutamic acid (Glu), Glycine (Gly), Arginine (Arg), Threonine (Thr), Alanine (Ala), Proline (Pro), Tyrosine (Tyr), Valine (Val), Methionine (Met), Lysine (Lys), Isoleucine (Ile), Leucine (Leu), Phenylalanine (Phe) Not given Antioxidation and antihypertension
Asian swamp eels [30] Not given Not given Asp, Glu, Lys, His, Arg, Asn, Gln, Ser and Thr Not given Emulsifier and stabilizer in food products
Sharks [31] Mice Not given Asn, Thr, Ser, Glu, Pro, Gly, Ala, Val, Cys, Met, Leu,Ile, Tyr, Phe, His, Lys, Arg, Hyp. <800 Da Osteoblast proliferation
Chicken Sternal cartilage [32] Not given II Glu, Ala, Pro, and Hyp,Cys, Met, Ile, Tyr, Phe, His 245 KDa Type II collagen
Chicken Heads (gelatin) [33] Not given Not given Not given Not given Good use of by-product
Skin (gelatin) [34] Not given B Hydroxyproline Not given Good use of by-product
Frog Rana chensinensis skin [35] Not given Not given Ala, Arg, Asp, Cys, Glu, Gly, His, Iso, Leu, Lys, Met, Phe, Hyp, Pro, Ser, Thr Tyr, Val 106 KDa Food stuff and medical
Duck Breast [36] Not given Not given Asp, Thr, Ser, Glu, Gly, Ala, Cys, Val, Met, Ile, Leu, Tyr, Phe, Lys, His, Arg, Pro 491–715 Da Antioxidant
Sheep and lambs Bone, cartilage, carcass trimmings and meat [37] Not given I Not given 5 < MW < 100 KDa Good use of by-product
Bees Royal Jelly [38] Drosophila Not given Gly, Glu, asp, Arg, Pro, Leu, Ala and Val <1 KDa Anti-oxidative, anti-aging